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There is no substitute for a practitioner's evaluation and further diagnostic tests, and it may be sensible to advise most (low-to-average-risk) patients against performing BSE, aside from noting breast changes (i.

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It can be age-related and associated with the postmenopausal decline in estrogen levels, or related to calcium and vitamin D insufficiency.

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Copyright 2016 Truven Health Analytics, Inc.

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Like tamoxifen, the first effective preventive for the disease, it also bolsters bones.

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Breast enlargement was unilateral in 5 cases; its duration ranged from a few weeks (7 cases) to several years (5 cases).

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Raloxifene is approved for the prevention and treatment of osteoporosis, and shows promise as a breast cancer prevention drug.

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Several of the corepressors shown to affect estrogen signaling may have the potential to be involved in antagonist signaling as well, provided that their mechanisms of repression are not due to anti-coactivator function by occupying the hydrophobic NR box site.

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